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AN54.1-4 | Radiodiagnosis — Part 2
Barium Studies — GI Tract Imaging (AN54.3)
Barium sulfate is swallowed or introduced rectally to coat the mucosal surface and reveal detail of the GI tract. Single-contrast (barium only) or double-contrast (barium + air insufflation — better mucosal detail).
Barium Swallow:
Patient swallows barium under fluoroscopy. Evaluates: pharynx, oesophagus, gastro-oesophageal junction.
Indications: dysphagia, oesophageal stricture, achalasia, pharyngeal pouch, hiatus hernia, carcinoma of oesophagus.
Key findings: bird-beak appearance (achalasia), rat-tail narrowing (carcinoma), mucosal irregularity, reflux.
Barium Meal:
Evaluates stomach and duodenum (1st–3rd parts).
Key findings: Barium niche (ulcer crater), filling defect (tumour), deformity of duodenal cap (cloverleaf deformity in chronic duodenal ulcer disease), mucosal pattern.
Barium Enema:
Barium introduced per rectum. Evaluates colon (large intestine from rectum to caecum).
Double-contrast technique preferred for mucosal detail.
Key findings: apple-core (napkin-ring) lesion = colonic carcinoma; thumbprinting = ischaemic colitis or inflammatory bowel disease; diverticular disease (outpouchings); strictures.
Cholecystography (Oral Cholecystogram):
Oral contrast is absorbed from gut → excreted in bile → concentrates in gall bladder (if functioning). Now largely replaced by ultrasound. Still asked in exams.
Assesses: gall bladder function, radiolucent gallstones (filling defects).
Intravenous Pyelography (IVP / IVU):
IV iodinated contrast excreted by kidney → visualises pelvicalyceal system, ureter, urinary bladder.
Key images: nephrogram (parenchyma), pyelogram (collecting system), ureterogram, cystogram.
Key findings: hydronephrosis (delayed drainage, dilated pelvicalyceal system), filling defects (stone, tumour), ureteric deviation, bladder outline.
Now supplemented/replaced by CT KUB (CT urogram) for stone disease.
Hysterosalpingography (HSG):
Iodinated contrast injected through cervix → opacifies uterine cavity and fallopian tubes → spills into peritoneum if tubes are patent.
Indications: infertility workup (tubal patency assessment), intrauterine pathology (fibroids, polyps, septum), Asherman syndrome.
Key findings: tubal block (contrast doesn't spill), uterine filling defects, tubal hydrosalpinx.
SELF-CHECK
A barium meal examination shows a persistent outpouching (niche) in the duodenal cap with surrounding mucosal convergence. What is the most likely diagnosis?
A. Duodenal carcinoma
B. Duodenal ulcer
C. Crohn's disease of the duodenum
D. Hiatus hernia
Reveal Answer
Answer: B. Duodenal ulcer
A "niche" on barium meal (persistent crater that retains barium) with surrounding radiating mucosal folds is the classic appearance of a peptic ulcer — in the duodenum most commonly in the duodenal cap (bulb/1st part). Carcinoma would show irregular filling defect, not a niche. Hiatus hernia is a gastro-oesophageal junction finding.
ERCP, CT Abdomen, MRI, and Arteriography (AN54.4)
ERCP (Endoscopic Retrograde Cholangio-Pancreatography):
Combines endoscopy + fluoroscopy. Endoscope passed to second part of duodenum → cannulate the ampulla of Vater → inject contrast → outline biliary tree and pancreatic duct.
Diagnostic + therapeutic: remove CBD stones (sphincterotomy + stone extraction), place stents for biliary strictures, biopsy ampullary tumours.
Key findings: CBD stone (filling defect), biliary stricture, pancreatic duct dilation or stricture (chronic pancreatitis), cholangiocarcinoma.
Replaced diagnostically by MRCP (non-invasive) but ERCP remains gold standard for therapy.
CT Abdomen:
Multi-slice CT provides rapid imaging of all abdominal structures.
Uses in abdomen: acute abdomen (appendicitis, diverticulitis), trauma (solid organ injury, haemoperitoneum), tumour staging, AAA (abdominal aortic aneurysm), pancreatitis, inflammatory bowel disease.
CT KUB (non-contrast): stone disease — sensitive for calculi >2 mm.
Triple-phase CT liver: plain + arterial + portal venous phases — characterises hepatic lesions (HCC, metastases, haemangioma).
MRI Abdomen:
Superior soft tissue contrast, no radiation. Preferred for:
• MRCP — non-invasive biliary and pancreatic ductal imaging (replaced diagnostic ERCP)
• MRI liver — characterisation of liver lesions (diffusion, T1/T2 characteristics)
• MRI rectum — staging of rectal carcinoma (pre-operative planning — local invasion, lymph nodes)
• MRI pelvis — uterine/ovarian pathology, endometriosis, fistulae
Arteriography (DSA / CT Angiography):
• Coeliac axis angiography — maps hepatic, splenic, left gastric arteries; pre-operative vascular mapping; embolisation for haemorrhage
• Mesenteric angiography — acute GI bleed localisation; mesenteric ischaemia
• Renal arteriography — renal artery stenosis (renovascular hypertension); pre-embolisation for AVM
• Portal venography — portal hypertension assessment, TIPS procedure guidance
• CT angiography (CTA) is now often preferred over DSA for diagnosis.
SELF-CHECK
A 45-year-old woman with obstructive jaundice is evaluated for suspected CBD stones. Which investigation is MOST appropriate as the first non-invasive approach to image the biliary tree?
A. ERCP
B. MRCP
C. IVP
D. Barium meal
Reveal Answer
Answer: B. MRCP
MRCP (Magnetic Resonance Cholangiopancreatography) is the non-invasive gold standard for imaging the biliary tree and pancreatic duct. It has replaced diagnostic ERCP. ERCP is reserved for therapeutic purposes (stone removal, stent placement). IVP and barium meal do not visualise the biliary tree.
CLINICAL PEARL
Rigler's Sign vs. Gas under Diaphragm:
On a supine plain X-ray abdomen, free intraperitoneal air cannot rise above the diaphragm — it distributes around bowel loops. Rigler's sign (double-wall or bowel wall sign) is seen: gas on both sides of the bowel wall, making the wall visible as a thin line. On an erect film, gas collects under the diaphragm. In a patient who cannot stand, a left lateral decubitus film (patient lies on left side, X-ray taken horizontally) shows free air above the liver — a highly sensitive sign of perforation.
ALARA Principle (As Low As Reasonably Achievable):
Radiation from X-rays and CT carries a small cancer risk. In young patients and pregnant women, prefer ultrasound (no radiation) or MRI for non-urgent evaluation. CT is reserved for situations where speed and anatomical detail outweigh the radiation risk (trauma, acute abdomen).