Page 8 of 17

SU30.3-5 | Epididymo-Orchitis, Varicocele and Hydrocele — SDL Guide (Part 2)

Principles of Management

Treatment follows the diagnosis, with the safety net that any unresolved suspicion of torsion goes to theatre. Epididymo-orchitis is treated with empirical antibiotics chosen by the likely organism — covering Chlamydia/gonococcus in sexually active young men (with partner treatment and STI counselling) and urinary coliforms in older men or those with urinary tract disease — together with analgesia, scrotal support, rest and, where relevant, treatment of any underlying obstruction; if torsion cannot be confidently excluded, the patient undergoes urgent surgical exploration rather than a trial of antibiotics. Varicocele is often managed conservatively with reassurance and a scrotal support when it is asymptomatic and fertility is not in question; intervention — surgical varicocelectomy (ligation of the dilated veins) or radiological embolisation — is reserved for significant pain, a varicocele causing testicular atrophy in an adolescent, or selected subfertile men with abnormal semen parameters; and any suspicious right-sided or non-decompressing varicocele is investigated for an underlying renal/retroperitoneal cause. Hydrocele in an adult that is small and asymptomatic may simply be observed; a large, tense or symptomatic primary hydrocele is treated surgically (e.g. Jaboulay's procedure — eversion of the sac — or Lord's plication), which is preferred to repeated aspiration; a secondary hydrocele is managed by treating its cause (infection, and crucially any underlying tumour) — one must never simply aspirate a hydrocele and reassure when a testicular tumour beneath it has not been excluded. In children, a congenital (communicating) hydrocele often resolves spontaneously by about two years and is otherwise treated by herniotomy (ligation of the patent processus vaginalis), not by aspiration.

comparison table of epididymo-orchitis, varicocele and hydrocele by definition, key clinical sign, principal investigation and main management
comparison table of epididymo-orchitis, varicocele and hydrocele by definition, key clinical sign, principal investigation and main management — click to enlarge

Provided image

ConditionDefinitionKey clinical signPrincipal investigationMain management
Epididymo-orchitisInfection/inflammation of epididymis ± testisTender swelling, fever, Prehn's sign positive, reflex preservedUrinalysis/culture + STI screen; Doppler USOrganism-directed antibiotics, analgesia, scrotal support, partner treatment; explore if torsion not excluded
VaricoceleDilated pampiniform plexus (usually left)'Bag of worms', worse standing, decompresses lyingStanding exam/Valsalva; semen analysis; image new/right-sidedReassurance/support; varicocelectomy or embolisation for pain/atrophy/subfertility
HydroceleSerous fluid within the tunica vaginalisTransilluminant, can get above itTransillumination; ultrasound to assess testisObserve (small); Jaboulay/Lord's surgery; treat the cause of a secondary hydrocele (exclude tumour)

CLINICAL PEARL

In every acutely painful scrotum, exclude testicular torsion FIRST — do not let a fever or dysuria lull you into calling it epididymo-orchitis, because torsion is a time-critical emergency (best salvage within about 6 hours) and a Doppler ultrasound must never delay surgical exploration when the diagnosis is clinically suspected. Two more habits save errors: never aspirate a hydrocele and reassure without excluding an underlying testicular tumour (treat the cause of a secondary hydrocele), and treat a new or non-decompressing right-sided varicocele as a red flag for a renal or retroperitoneal mass until imaging proves otherwise.

Check Your Understanding

Bring the three patients from the hook back and run the reasoning. The 28-year-old with a two-day tender, hot, swelling hemiscrotum, fever, dysuria and relief on elevation has epididymo-orchitis: Prehn's sign is positive and the cremasteric reflex is preserved, so you would screen the urine and (given his age) for STIs, start organism-directed antibiotics with analgesia and scrotal support, and treat his partner — reasoning from 'gradual, febrile, eases on lifting' to 'infection, treat appropriately'. The 19-year-old with sudden, severe pain, a high-riding tender testis and an absent reflex has testicular torsion until proven otherwise: you would proceed to urgent surgical exploration without letting imaging delay theatre — reasoning from 'sudden, no relief, absent reflex, teenager' to 'emergency'. The 32-year-old with a soft, painless, transilluminant swelling you can get above has a hydrocele, which you would scan to exclude an underlying tumour before deciding between observation and surgery. Now self-test the competency directly. Can you give the applied anatomy behind the left-sided varicocele and the tunica-vaginalis origin of a hydrocele? Can you list the clinical features and the bedside signs (get-above-it, transillumination, Prehn's sign, cremasteric reflex, standing/Valsalva) that separate the three swellings — and torsion — from one another? Can you name the targeted investigations and the principles of management for each, including the rules to exclude torsion, exclude a tumour beneath a hydrocele, and image a suspicious varicocele? The questions that follow check these links.

SELF-CHECK

A 35-year-old is found to have a soft scrotal swelling that transilluminates brightly and above which the examining fingers can meet. What is the diagnosis, and what is the essential next step before reassurance?

A. Inguinoscrotal hernia — arrange urgent herniorrhaphy

B. Hydrocele — aspirate it in clinic and reassure

C. Hydrocele — perform ultrasound of the testis to exclude an underlying tumour (secondary hydrocele)

D. Varicocele — recommend a scrotal support only

Reveal Answer

Answer: C. Hydrocele — perform ultrasound of the testis to exclude an underlying tumour (secondary hydrocele)

A transilluminant scrotal swelling above which you can get is a hydrocele (you cannot get above an inguinoscrotal hernia). Before reassuring, the underlying testis must be assessed with ultrasound, because a hydrocele may be secondary to a testicular tumour. Simply aspirating and reassuring risks missing a cancer; aspiration is not the definitive treatment for a primary hydrocele either.

Interactive practice: Multiple Choice

Interactive practice: True / False