MI8.{1-2,4} | Genitourinary & Sexually Transmitted Infections — Graded Quiz

A 22-year-old sexually active woman presents with dysuria and frequency. Urine culture grows >10⁵ CFU/mL of a gram-positive coccus in clusters, coagulase-negative, that ferments mannitol and is novobiocin-resistant. Which statement about this organism's role in UTI is MOST accurate?

A 65-year-old man with type 2 diabetes is admitted with fever, rigors, and flank pain. He was catheterised for 3 days during a recent hospitalisation. Urine culture grows >10⁵ CFU/mL of a gram-negative rod that is oxidase-positive, non-lactose fermenting, and produces a distinctive grape-like odour. Which is the MOST appropriate initial antibiotic choice pending susceptibility results?

A pregnant woman at 14 weeks is found to have asymptomatic bacteriuria (E. coli 10⁵ CFU/mL) on routine antenatal urine culture. She is afebrile with no urinary symptoms. What is the MOST appropriate course of action?

A 24-year-old man presents with copious purulent urethral discharge and dysuria for 3 days. Gram stain of urethral discharge shows intracellular gram-negative diplococci within polymorphonuclear leucocytes. NAAT confirms the causative agent. The MOST appropriate treatment regimen, given current resistance patterns, is:

A 28-year-old commercial sex worker presents with a painful, soft, dirty-based ulcer with ragged undermined edges on the labia. She has tender, fluctuant unilateral inguinal lymphadenopathy (bubo). Dark-field microscopy is negative. Which organism is MOST likely responsible, and what is the recommended treatment?

A 30-year-old woman presents with vaginal discharge and vulvar pruritus. Examination reveals curdy white discharge and erythematous vaginal mucosa. KOH preparation shows budding yeast cells with pseudohyphae. She reports 3 similar episodes in the past 12 months. Which of the following predisposing factors is MOST directly responsible for recurrent vulvovaginal candidiasis?

A 35-year-old asymptomatic blood donor is found to have RPR reactive at 1:8. TPHA is also positive. He has no history of syphilis treatment. His CD4 count and HIV test are normal. What is the MOST likely stage of syphilis and the recommended treatment?

A newborn's blood VDRL at birth is reactive at 1:4. The mother was diagnosed with syphilis at 32 weeks and received a full course of benzathine penicillin. The newborn is asymptomatic. What is the CORRECT interpretation of the newborn's VDRL result?

A 26-year-old man presents for HIV testing 3 weeks after a high-risk sexual exposure. Which fourth-generation HIV test strategy is CORRECT for this timing?

A 28-year-old pregnant woman at 8 weeks gestation is screened and found to be HBsAg-positive, HBeAg-positive, and anti-HBc-positive. Her newborn is at HIGHEST risk for which outcome if not given immediate prophylaxis?

A 19-year-old woman presents with a vaginal discharge that is homogeneous, grey-white, and fishy-smelling. Wet mount shows epithelial cells studded with coccobacilli ('clue cells'). pH of vaginal secretion is 5.5. Whiff (amine) test is positive. Which organism is the PRIMARY driver of this condition, and what is the recommended treatment?

A 38-year-old male truck driver presents with haematuria (blood in urine seen at the END of micturition), without dysuria or fever. He reports spending the past 10 years near freshwater bodies in Bihar. Urine microscopy reveals oval ova with a terminal spine. Which of the following is the MOST likely diagnosis and appropriate treatment?